• 3They Don't Care (aurelien2022.substack.com)
  by iamnothere 3 hours ago | discuss
• 4Moderna surges as Merck-partnered melanoma vaccine cuts recurrence in trial (reuters.com)
  by consumer451 3 hours ago | discuss
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  by alderik_ 4 hours ago | discuss
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  by fskroes_is_me 4 hours ago | discuss
• 4Show HN: My Mac slept through its cron jobs, so I made goguma, a menu bar app (github.com)
  by junnam586 4 hours ago | 2 comments
• 298Moderna reports first positive Phase 3 for mRNA neoantigen therapy in melanoma (twitter.com)
  by heydenberk 4 hours ago | 118 comments
• 2Where the Tool Stops and I Begin (rivetrune.com)
  by rivetrune 4 hours ago | 1 comments
• 5Source-Code Availability and How I Became Radicle-Ized (kristoff.it)
  by h1watt 4 hours ago | discuss
• 17AI Has Plunged the Book Publishing Industry into Utter Chaos (wsj.com)
  by galsapir 4 hours ago | 17 comments
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  by OutOfHere 4 hours ago | 1 comments
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  by pbui 4 hours ago | 5 comments
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  by flail 4 hours ago | discuss
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  by geerlingguy 4 hours ago | 1 comments
• 3AWS Powers PyPI and the PSF (pyfound.blogspot.com)
  by lumpa 4 hours ago | discuss
• 2State of Devs, a developer survey about career, health, hobbies, and politics (survey.devographics.com)
  by sgdesign 4 hours ago | discuss
• 26Moderna and Merck say mRNA cancer vaccine succeeded in late-stage melanoma trial (statnews.com)
  by cwwc 4 hours ago | 1 comments
• 2I read the ingredient list of 35000 UK supermarket products so you don't have to (plainfood.co.uk)
  by camzbarber 4 hours ago | 2 comments
• 4Show HN: Marginal – See which customers and features drive your AI API costs (marginalhq.com)
  by jithinlalk25 4 hours ago | discuss
• 2Intent Containers (armoriq.substack.com)
  by ketanbj 4 hours ago | discuss
• 163PostgreSQL for Everything (raphaelbauer.com)
  by karlmush 4 hours ago | 116 comments
• 2OpenADMET: Response to Pat Walters (fbdd-lit.blogspot.com)
  by surprisetalk 4 hours ago | discuss
• 5Show HN: SparkleChinese – Learn Chinese while you browse (sparklechinese.com)
  by tommy_guo 4 hours ago | discuss
• 1Martin Fowler: Fragments from August 18 (martinfowler.com)
  by jreynar 4 hours ago | discuss
• 3Big Little Hexagon (johndcook.com)
  by ibobev 4 hours ago | discuss
• 1ValleyRAT campaign targets Indian taxpayers with fake GSTR-3B overdue notice (blog.himanshuanand.com)
  by unknownhad 4 hours ago | discuss
• 1What building a Reactigotchi can teach you about an applications "memory" (2025) (erinmikailstaples.com)
  by mooreds 4 hours ago | discuss
• 1Using Vue.js with Electron (xnacly.me)
  by ibobev 4 hours ago | discuss
• 1Race-free handle inheritance, maybe (purplesyringa.moe)
  by ibobev 4 hours ago | discuss
• 1Amazon set to expand drone delivery of lightweight packages to 500 US cities (apnews.com)
  by geox 4 hours ago | discuss
• 2I Built a Password Manager with No Back End. It Works Better Than I Expected (kryptprivacy.com)
  by clausemint 4 hours ago | discuss